https://nordot.app/1259230702735360906
https://www.dpa-international.com/trends-and-features/urn:newsml:dpa.com:20090101:250203-99-797851/
https://www.yahoo.com/news/alzheimers-breakthrough-closer-brain-oxygen-193314599.html
A team of doctors and scientists have found “clear evidence” of a cause of neurodegeneration in people with Alzheimer’s disease.
“Changes in the orchestration of brain oxygenation dynamics and neuronal function in Alzheimer’s disease contribute to the neurodegeneration,” according to researchers from Lancaster University and the University Medical Centre in Ljubljana.
Published on February 3 in the journal Brain Communications, the insights could help doctors and patients to better understand the disease, the causes of which “remain elusive,” the researchers say.
The team said the “neurovascular dynamics” they uncovered “have potential for early diagnosis” and could prove to be “a marker of disease progression” and help with “evaluating the effect of interventions.”
“Alzheimer’s can be hypothesised as being a result of the brain not being appropriately nourished via the blood vessels,” said Aneta Stefanovska of the University of Lancaster, whose team’s research comes as the latest in a series of new insights into Alzheimer’s and dementia that have raised hopes of understanding the conditions better and inching closer to coming up with treatments.
In late January, the American Academy of Neurology published research suggesting an association between high cholesterol levels and the likelihood of developing dementia.
Annual measurements of “fluctuating cholesterol” could prove to be “a new biomarker for identifying people at risk of dementia,” said Zhen Zho of Monash University in Australia.
Around the same time a team of French and Italian scientists said they had found “a real breakthrough” for analysing the human gut and how x-rays can “provide clues on the processes that link the gut neurons with those in the brain and may trigger Alzheimer’s.”
The technique “could be pivotal in early detection and prognosis of the disease,” said Alessia Cedola of the Institute of Nanotechnology in Rome, whose team’s research was published in the journal Science Advances.
